{"title":"Protease","description":"\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"BreadcrumbList\",\n  \"itemListElement\": [\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 1,\n      \"name\": \"Home\",\n      \"item\": \"https:\/\/plenthera.com\/\"\n    },\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 2,\n      \"name\": \"Categories\",\n      \"item\": \"https:\/\/plenthera.com\/collections\/\"\n    },\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 3,\n      \"name\": \"Protease\",\n      \"item\": \"https:\/\/plenthera.com\/collections\/protease\/\"\n    }\n  ]\n}\n\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"CollectionPage\",\n  \"name\": \"Protease at Plenthera\",\n  \"description\": \"Protease — protein-digesting enzymes for protein digestion. At Plenthera in Aminolase TPA®, in digestive complexes and in systemic enzyme complexes.\",\n  \"url\": \"https:\/\/plenthera.com\/collections\/protease\/\",\n  \"inLanguage\": \"en\",\n  \"isPartOf\": {\n    \"@type\": \"WebSite\",\n    \"name\": \"Plenthera\",\n    \"url\": \"https:\/\/plenthera.com\/\"\n  },\n  \"about\": {\n    \"@type\": \"Thing\",\n    \"name\": \"Protease\",\n    \"description\": \"Protease is a collective name for enzymes that break down protein into absorbable amino acids and peptides.\"\n  }\n}\n\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is protease?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A protein-digesting enzyme (collective name). Pepsin, trypsin and chymotrypsin are produced by the body; bromelain and papain are plant-based.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"When should you take protease?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"With protein-rich meals. Systemic enzyme complexes between meals on an empty stomach.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e\n\u003carticle\u003e\n\u003cp\u003e\u003cem\u003eWritten by the Plenthera team (trained in orthomolecular nutrition). Scientifically reviewed in April 2026. Last updated: 22 September 2026.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eProtease is not a single enzyme but a family — pepsin, trypsin, bromelain, papain — each of which breaks down protein into absorbable amino acids and peptides. For those who eat a lot of protein (athletes, older people, meat-heavy diet), protease supplementation can be useful. At Plenthera you will find \u003ca href=\"\/en-es\/collections\/protease\"\u003eprotease\u003c\/a\u003e in Aminolase TPA® (protease mix for protein digestion), in broad digestive complexes and in the systemic enzyme complexes from Arthur Andrew Medical.\u003c\/p\u003e\n\u003cnav aria-label=\"Table of contents\"\u003e\n\u003ch2\u003eTable of contents\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"#vergelijking\"\u003eWhich protease suits you?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wat-is-protease\"\u003eWhat is protease?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wetenschap\"\u003eWhat does science say?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#vormen\"\u003eThe protease forms at Plenthera\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#hoe-gebruik\"\u003eHow do you use protease?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#mythes\"\u003eMyths and misconceptions about protease\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#combineren\"\u003eCombining protease with other supplements\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#faq\"\u003eFrequently asked questions\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#bronnen\"\u003eSources\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/nav\u003e\n\u003csection\u003e\n\u003ch2 id=\"vergelijking\"\u003eWhich protease suits you?\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eBest for\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eAminolase TPA® — protease mix (Arthur Andrew Medical)\u003c\/td\u003e\n\u003ctd\u003eTargeted protein digestion with protein-rich meals and protein shakes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIn a digestive complex (Devigest ADS®, Doctor's Best Digestive Enzymes)\u003c\/td\u003e\n\u003ctd\u003eBroad digestion with every meal\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSystemic enzyme complex (Neprinol AFD®, Fibrovera AHS®, Serrétia®)\u003c\/td\u003e\n\u003ctd\u003eOn an empty stomach between meals\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (separate)\u003c\/td\u003e\n\u003ctd\u003eProtein digestion + pineapple protease\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wat-is-protease\"\u003eWhat is protease?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eProtease is a collective name for enzymes that break down protein — pepsin, trypsin and chymotrypsin (produced by the body), bromelain (from pineapple), papain (from papaya).\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eProtein digestion begins in the stomach with pepsin (activated by stomach acid) and continues in the small intestine with trypsin and chymotrypsin from the pancreas. For those who eat a lot of protein — athletes with a high protein intake, a meat-heavy diet, older people with reduced own production — protease supplementation can reduce the load on the body's own system.\u003c\/p\u003e\n\u003cp\u003eSupplements often combine several proteases for a broad pH range. Plant-based bromelain (from pineapple) works mainly in the gut; pepsin works in stomach acid. A protease mix covers the entire digestive tract.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wetenschap\"\u003eWhat does science say?\u003c\/h2\u003e\n\u003cp\u003eThe action of proteases (splitting proteins into peptides and amino acids) is biochemically well documented; activity is expressed in HUT units. Research into supplementation focuses mainly on people with reduced own enzyme production. We describe the mechanism, without claims of effect.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"vormen\"\u003eThe protease forms at Plenthera\u003c\/h2\u003e\n\u003ch3\u003eAminolase TPA® — 90 capsules\u003c\/h3\u003e\n\u003cp\u003eProtease mix from Arthur Andrew Medical, developed for the digestion of dietary protein. One capsule with protein-rich meals or protein shakes.\u003c\/p\u003e\n\u003ch3\u003eProtease in a digestive complex\u003c\/h3\u003e\n\u003cp\u003eDevigest ADS® (Arthur Andrew Medical, 180 capsules, also 3×180) with 50,000 HUT proteases per serving, Doctor's Best Digestive Enzymes (16 enzymes, 90 capsules) and Syntol AMD® (enzyme complex with proteases plus live cultures, 360 capsules).\u003c\/p\u003e\n\u003ch3\u003eSystemic enzyme complexes\u003c\/h3\u003e\n\u003cp\u003eNeprinol AFD® (90, 150 and 300 capsules), Fibrovera AHS® (90 capsules) and Serrétia® (serrapeptase 250,000 SPU, 90 and 180 capsules) — proteases taken on an empty stomach between meals.\u003c\/p\u003e\n\u003ch3\u003eBromelain (pineapple protease)\u003c\/h3\u003e\n\u003cp\u003eA separate category — see our \u003ca href=\"\/en-es\/collections\/bromelaine\"\u003ebromelain category\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eOther forms on the market\u003c\/h3\u003e\n\u003cp\u003eWe do not currently stock single protease capsules without a complex, or animal pancreatin.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"hoe-gebruik\"\u003eHow do you use protease?\u003c\/h2\u003e\n\u003cp\u003eA simple basic approach for protease:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eWith a protein-rich meal — follow the dosage on the label (Aminolase TPA®: 1 capsule).\u003c\/li\u003e\n\u003cli\u003eSystemic enzyme complexes (Neprinol AFD®, Fibrovera AHS®, Serrétia®): between meals, on an empty stomach.\u003c\/li\u003e\n\u003cli\u003eFor broad coverage: a digestive complex with every meal.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"mythes\"\u003eMyths and misconceptions about protease\u003c\/h2\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 1: \"Protease makes protein more absorbable for muscle growth.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eHealthy people digest protein well themselves. With reduced own production, a supplement can help.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 2: \"Higher protease doses yield more amino acids.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eAbove a certain dose, extra protease does not translate into extra absorption.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 3: \"Protease and bromelain are the same.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBromelain is a protease — a specific one from pineapple. Usually several proteases are blended.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"combineren\"\u003eCombining protease with other supplements\u003c\/h2\u003e\n\u003cp\u003eProtease is often combined. Popular combinations:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-es\/collections\/bromelaine\"\u003eBromelain\u003c\/a\u003e: an extra protein enzyme from pineapple.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-es\/collections\/spijsverteringsenzymen\"\u003eDigestive enzyme complex\u003c\/a\u003e: broad coverage.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-es\/collections\/vegan-proteine\"\u003eVegan Protein\u003c\/a\u003e: for the sports protein cluster.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-es\/collections\/levende-culturen\"\u003eProbiotics\u003c\/a\u003e: gut theme.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"faq\"\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eA protein-digesting enzyme (collective name).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen should you take protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWith a protein-rich meal.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtease for sport?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor recovery: a systemic complex between meals. With a meal or shake: Aminolase TPA®.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow much protease per day?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFollow the label.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is HUT?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe unit for protease activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVegan protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMicrobial\/plant-based: yes — the Arthur Andrew Medical formulas are microbial and vegan.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDifference between bromelain and protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBromelain is a specific protease from pineapple.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes protease have side effects?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenerally well tolerated.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePlant-based vs animal protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePlant-based\/microbial: vegan. Animal (pancreatin): classic, not stocked by us.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtease for bloating?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMay help with protein-related complaints.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"bronnen\"\u003eSources\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRoxas M., \"The role of enzyme supplementation in digestive disorders\", Altern Med Rev (2008).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This text is for informational purposes only and does not replace medical advice. Protease is a food supplement, not a medicine. If in doubt or if you take medication, we recommend consulting a doctor or orthomolecular therapist first.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/article\u003e","products":[{"product_id":"arthur-andrew-neprinol-afd-150-caps","title":"Neprinol AFD® – Enzyme Complex – 150 capsules","description":"\u003cp\u003eEnzyme complex with nattokinase and serrapeptase. Neprinol AFD® by Arthur Andrew Medical combines nattokinase (15,000 FU), serrapeptase (45,000 SPU) and a broad enzyme complex (papain, bromelain, lipase, proteases) with coenzyme Q10, amla extract and rutin. Plant-based Acid Armor capsules — acid-resistant without phthalates. Non-GMO, vegetarian, Kosher. 150 capsules, enough for 50–75 daily doses.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767386026329,"sku":"AAM1071","price":82.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/Neprinol150caps.webp?v=1783521833"},{"product_id":"arthur-andrew-neprinol-afd-300-caps","title":"Neprinol AFD® – Enzyme Complex – 300 capsules","description":"\u003cp\u003eNeprinol AFD® combines nattokinase (15,000 FU), serrapeptase (45,000 SPU), proteinases, papain, bromelain and lipase — supplemented with magnesium, amla extract, rutin and coenzyme Q10. Packed in acid-resistant Acid Armor capsules made from plant cellulose, without phthalates. Non-GMO, Kosher, vegetarian. 300 capsules per pack.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767386845529,"sku":"AAM1070","price":144.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/AAMNeprinol300_ec7cb2f6-97d1-4a55-9f4c-7567b2cef98b.webp?v=1783581906"},{"product_id":"arthur-andrew-serretia-180-caps","title":"Serretia® – Serrapeptase 250,000 SPU – 180 capsules","description":"\u003cp\u003ePure serrapeptase — without additives. Arthur Andrew Medical Serretia® contains 250,000 SPU serrapeptase per dose (2 capsules), packed in plant-based Acid Armor capsules that protect the enzymes from stomach acid. Vegetarian (AVA), Kosher (Star-K), Non-GMO. 180 capsules, enough for 90 doses.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767388746073,"sku":"AAM1120","price":104.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/Serretia180AAM.webp?v=1783519879"},{"product_id":"arthur-andrew-serretia-90-caps","title":"Serrétia® – 90 capsules","description":"\u003cp\u003eSerrétia® is a pure serrapeptase supplement by Arthur Andrew Medical — 125,000 SPU per capsule (250,000 SPU per 2 capsules) in an Acid Armor capsule that protects enzymes from stomach acid. The pack contains 90 plant-based capsules, enough for 45 to 90 doses.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767389827417,"sku":"AAM1121","price":52.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/AAMSerretia90.webp?v=1783520095"},{"product_id":"arthur-andrew-syntol-amd-360-caps","title":"Syntol AMD® – 360 capsules","description":"\u003cp\u003eLive cultures, fibre and enzymes in one formula. Syntol AMD by Arthur Andrew Medical combines 13.6 billion CFU of spore-forming and lactic acid-producing microorganisms with dietary fibre (isomalto-oligosaccharide) and an enzyme complex (including serrapeptase, amylase, cellulase). Plant-based Acid Armor capsules protect the contents from stomach acid. Free from gluten, soy and dairy. 360 capsules, enough for approx. 90 daily doses.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767408046425,"sku":"AAM1140","price":124.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/AAMSyntol.webp?v=1783523118"},{"product_id":"arthur-andrew-neprinol-afd-90-caps","title":"Neprinol AFD® – Enzyme Complex – 90 capsules","description":"\u003cp\u003eNeprinol AFD® is an enzyme complex in capsules with nattokinase, serrapeptase, proteinases, papain, bromelain, and lipase, supplemented with magnesium, amla extract, rutin, and coenzyme Q10. The formula is available in acid-resistant Acid Armor capsules made of vegetable cellulose, without coating.\u003c\/p\u003e\n\u003cp\u003eAcid Armor Capsule • 90 capsules per package • Non-GMO • Kosher • Vegetarian\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767412240729,"sku":"AAM1073","price":57.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/AAMNeprinol90_f0116be4-2933-412c-a815-e82db38fdcc9.webp?v=1783520748"},{"product_id":"arthur-andrew-devigest-ads-180-caps","title":"Devigest ADS® – Enzyme Formula – 180 capsules","description":"\u003cp\u003eA broad spectrum of digestive enzymes in one formula. Devigest ADS® by Arthur Andrew Medical combines peptidase DPP-IV, lactase (2,000 ALU), alpha-galactosidase and an extensive enzyme complex (including bromelain, lipase and papain). Plant-based capsules, free from gluten, soy and dairy. 180 capsules, enough for 90 servings.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767413518681,"sku":"AAM1010","price":50.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/Devigest_7e278132-1701-4730-bdcc-e96d0772e09c.webp?v=1784278464"},{"product_id":"arthur-andrew-fibrovera-ahs-90-cap","title":"Fibrovera AHS® – 90 capsules","description":"\u003cp\u003eFibrovera® AHS combines an enzyme blend (serrapeptase, nattokinase NSK®, bromelain) with a herbal blend (GLA, DIM, 5-HTP, black cohosh, dong quai) and 50 mg vitamin B6 per capsule — developed by Arthur Andrew Medical. The jar contains 90 capsules, enough for 30 to 90 doses depending on intake.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56768708116825,"sku":"AAM1040","price":69.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/Fibrovera.webp?v=1783589042"},{"product_id":"arthur-andrew-aminolase-tpa-90-caps","title":"Aminolase TPA® – 90 capsules","description":"\u003cp\u003eAminolase® TPA is an acid-stable protease enzyme complex by Arthur Andrew Medical, specifically formulated for use with protein-rich meals and protein shakes. Each capsule contains 250 mg Acid Stable Protease Blend in a plant-based cellulose capsule — the jar contains 90 capsules.\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56768772866393,"sku":"AAM1000","price":49.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/Aminolase.webp?v=1783585554"},{"product_id":"doctors-best-digestive-enzymes-90-vcaps","title":"Digestive Enzymes – 16 enzymes – 90 vegetarian capsules","description":"\u003cp\u003e\u003cspan\u003eDoctor's Best Digestive Enzymes is a broad-spectrum formula with sixteen digestive enzymes from microbial sources, targeting carbohydrates, fats, proteins, fibre and bean sugars. The formula also contains 1 billion CFU Bacillus subtilis (live micro-organisms), a spore-forming strain that withstands production and storage. Everything comes in one plant-based capsule of about 450 mg enzyme blend. 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