{"title":"MSM","description":"\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"BreadcrumbList\",\n  \"itemListElement\": [\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 1,\n      \"name\": \"Home\",\n      \"item\": \"https:\/\/plenthera.com\/\"\n    },\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 2,\n      \"name\": \"Minerals\",\n      \"item\": \"https:\/\/plenthera.com\/collections\/mineralen\"\n    },\n    {\n      \"@type\": \"ListItem\",\n      \"position\": 3,\n      \"name\": \"MSM\",\n      \"item\": \"https:\/\/plenthera.com\/collections\/msm\"\n    }\n  ]\n}\n\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"CollectionPage\",\n  \"name\": \"MSM at Plenthera\",\n  \"description\": \"MSM (methylsulfonylmethane) in vegan capsules from Plantforce and in Glucosamine Chondroitin MSM with OptiMSM® from Doctor's Best.\",\n  \"url\": \"https:\/\/plenthera.com\/collections\/msm\",\n  \"inLanguage\": \"en\",\n  \"isPartOf\": {\n    \"@type\": \"WebSite\",\n    \"name\": \"Plenthera\",\n    \"url\": \"https:\/\/plenthera.com\/\"\n  },\n  \"about\": {\n    \"@type\": \"Thing\",\n    \"name\": \"MSM\",\n    \"alternateName\": [\n      \"Methylsulfonylmethane\",\n      \"Dimethyl sulfone\",\n      \"DMSO2\"\n    ],\n    \"description\": \"MSM is an organic sulphur compound that occurs in small amounts in food.\"\n  }\n}\n\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is MSM?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"MSM (methylsulfonylmethane) is an organic sulphur compound. It occurs in small amounts in vegetables, fruit, milk, coffee and tea. As a supplement, it is usually taken in capsules or as a powder.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How much MSM should I take per day?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Follow the dosage on the label. For Plantforce Vegan MSM, that is 2 to 3 capsules per day (1,600–2,400 mg). For Glucosamine Chondroitin MSM from Doctor's Best, it is 4 capsules per day (1,000 mg MSM).\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is OptiMSM®?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"OptiMSM® is a brand name for MSM that is purified by distillation. It is contained in Glucosamine Chondroitin MSM from Doctor's Best.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Is MSM vegan?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"MSM itself is. Plantforce Vegan MSM is fully vegan. Glucosamine Chondroitin MSM from Doctor's Best is not: the glucosamine comes from shellfish and the chondroitin from beef.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"When should I take MSM?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Preferably with a meal and a glass of water. Optionally split the daily dose over two moments.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"Does MSM have side effects?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"In studies, MSM is well tolerated at common dosages; mild gastrointestinal complaints are sometimes reported. If pregnant, breastfeeding or taking medication, consult your doctor first.\"\n      }\n    }\n  ]\n}\n\u003c\/script\u003e\n\u003carticle\u003e\n\u003cp\u003e\u003cem\u003eWritten by the Plenthera team (trained in orthomolecular nutrition). Scientifically reviewed in October 2026. Last updated: 7 October 2026.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eMSM (methylsulfonylmethane) is an organic sulphur compound that occurs in small amounts in food. At Plenthera you will find \u003ca href=\"\/en-lu\/collections\/msm\"\u003eMSM\u003c\/a\u003e as pure, vegan capsules from the Danish brand Plantforce (800 mg per capsule) and in Glucosamine Chondroitin MSM from Doctor's Best, in which 1,000 mg OptiMSM® is combined with glucosamine and chondroitin.\u003c\/p\u003e\n\u003cnav aria-label=\"Table of contents\"\u003e\n\u003ch2\u003eTable of contents\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"#vergelijking\"\u003eWhich MSM suits you?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wat-is-msm\"\u003eWhat is MSM?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wetenschap\"\u003eWhat does science say about MSM?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#optimsm-en-de-kwaliteit-vraag\"\u003ePurity and OptiMSM®\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#vormen\"\u003eMSM at Plenthera and other forms on the market\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#hoe-gebruik\"\u003eHow do you use MSM?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#mythes\"\u003eMyths and misconceptions about MSM\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#combineren\"\u003eCombining MSM with other supplements\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#faq\"\u003eFrequently asked questions\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#bronnen\"\u003eSources\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/nav\u003e\n\u003csection\u003e\n\u003ch2 id=\"vergelijking\"\u003eWhich MSM suits you?\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003cth\u003eMSM per daily dose\u003c\/th\u003e\n\u003cth\u003eFeatures\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003ca href=\"\/en-lu\/collections\/plantforce-msm-twn\"\u003ePlantforce Vegan MSM, 200 capsules\u003c\/a\u003e (at Plenthera)\u003c\/td\u003e\n\u003ctd\u003e1,600–2,400 mg (2–3 capsules)\u003c\/td\u003e\n\u003ctd\u003e100% pure MSM, vegan, 800 mg per capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDoctor's Best Glucosamine Chondroitin MSM, 240 or 360 capsules (at Plenthera)\u003c\/td\u003e\n\u003ctd\u003e1,000 mg OptiMSM® (4 capsules)\u003c\/td\u003e\n\u003ctd\u003eWith 1,500 mg glucosamine and 1,200 mg chondroitin; contains shellfish and beef\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMSM powder (other forms on the market)\u003c\/td\u003e\n\u003ctd\u003eVariable\u003c\/td\u003e\n\u003ctd\u003eFlexible dosing, slightly bitter taste — we do not currently stock it\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wat-is-msm\"\u003eWhat is MSM?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMSM (methylsulfonylmethane, also dimethyl sulfone) is an organic sulphur compound with the formula (CH₃)₂SO₂. About 34% of the molecule is sulphur. MSM is not a vitamin or mineral, but a substance that occurs in small amounts in food.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSulphur is a building block of the amino acids methionine and cysteine and thus of many proteins, including keratin and collagen, and of glutathione. Most sulphur is obtained through protein-rich food. MSM itself is found in small amounts in vegetables, fruit, milk, coffee and tea.\u003c\/p\u003e\n\u003cp\u003eMSM in supplements is produced industrially and then purified; the end product is chemically identical to the MSM that occurs in food.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wetenschap\"\u003eWhat does science say about MSM?\u003c\/h2\u003e\n\u003cp\u003eMSM is mainly researched in relation to joint comfort and recovery after intensive exertion, and to a lesser extent for the skin. Studies have examined, among others, people with knee complaints due to wear and tear and athletes after heavy training, with dosages of about 1.5 to 6 grams per day. Many of these studies are small and short, and some examined MSM in combination with glucosamine or chondroitin. As a result, the findings cannot yet be translated into a fixed expectation for everyone.\u003c\/p\u003e\n\u003cp\u003eMore is known about safety: in studies, MSM is well tolerated at common dosages. Mild gastrointestinal complaints, headaches or a slightly energised feeling are sometimes reported.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"optimsm-en-de-kwaliteit-vraag\"\u003ePurity and OptiMSM®\u003c\/h2\u003e\n\u003cp\u003eAfter production, MSM is purified by crystallisation or distillation. In distillation, MSM is vaporised and condensed again, leaving impurities behind.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOptiMSM®\u003c\/strong\u003e is a brand name for MSM that is purified by distillation. It is contained in Glucosamine Chondroitin MSM from Doctor's Best. According to the label, Plantforce Vegan MSM consists of 100% pure MSM without additives, in a plant-based capsule.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"vormen\"\u003eMSM at Plenthera and other forms on the market\u003c\/h2\u003e\n\u003ch3\u003eVegan MSM, 200 capsules (Plantforce) — at Plenthera\u003c\/h3\u003e\n\u003cp\u003ePure MSM from the Danish brand Plantforce, 800 mg per capsule. Adults take 2 to 3 capsules per day (1,600–2,400 mg), preferably with a meal and a glass of water. From 12 years: start with 1 capsule per day. Free from gluten, soya and lactose; suitable for vegans. Distribution is handled by Plent B.V. Read more about the brand at \u003ca href=\"\/en-lu\/collections\/plantforce-msm-twn\"\u003ePlantforce MSM\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eGlucosamine Chondroitin MSM (Doctor's Best) — at Plenthera\u003c\/h3\u003e\n\u003cp\u003ePer daily dose of 4 capsules: 1,500 mg glucosamine hydrochloride potassium sulphate, 1,200 mg chondroitin sulphate and 1,000 mg MSM (OptiMSM®). Available with 240 and 360 capsules. The glucosamine comes from shellfish and the chondroitin from beef: not suitable for vegetarians, vegans and people with a shellfish allergy. If you use anticoagulants, consult your doctor first. Read more about glucosamine at \u003ca href=\"\/en-lu\/collections\/glucosamine\"\u003eglucosamine\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch3\u003eOther forms on the market\u003c\/h3\u003e\n\u003cp\u003eMSM powder offers flexible dosing and can be stirred into water or a drink; the taste is slightly bitter. There are also combinations of MSM with collagen or vitamin C and creams with MSM. We do not currently stock these.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"hoe-gebruik\"\u003eHow do you use MSM?\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eFollow the dosage on the label: 2–3 capsules of Plantforce Vegan MSM or 4 capsules of Glucosamine Chondroitin MSM per day.\u003c\/li\u003e\n\u003cli\u003eTake the capsules with a meal and a glass of water and optionally split them over two moments.\u003c\/li\u003e\n\u003cli\u003eDo not use the products at the same time without adding up the total amount of MSM.\u003c\/li\u003e\n\u003cli\u003eGive a supplement a number of weeks before you assess whether it suits you.\u003c\/li\u003e\n\u003cli\u003eIf pregnant, breastfeeding, taking medication (particularly anticoagulants) or with a shellfish allergy: consult your doctor first.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"mythes\"\u003eMyths and misconceptions about MSM\u003c\/h2\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 1: \"MSM is a miracle cure for joints.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eNot scientifically substantiated. Research is ongoing, but the studies are usually small and short.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 2: \"The more MSM, the better.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eIncorrect. More than the dosage on the label provides no demonstrated benefit and can cause gastrointestinal complaints.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 3: \"MSM is the same as sulphur from garlic or onion.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eNo. Garlic and onion contain other sulphur compounds, such as allicin and sulphides. MSM is a specific compound.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"combineren\"\u003eCombining MSM with other supplements\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-lu\/collections\/glucosamine\"\u003eGlucosamine\u003c\/a\u003e: the classic combination, as in the Doctor's Best formula.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-lu\/collections\/vitamine-c\"\u003eVitamin C\u003c\/a\u003e: vitamin C contributes to normal collagen formation for the normal function of cartilage.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-lu\/collections\/collageen\"\u003eCollagen\u003c\/a\u003e: often used together in a routine for skin and connective tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-lu\/collections\/magnesium\"\u003eMagnesium\u003c\/a\u003e: magnesium contributes to normal muscle function.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"\/en-lu\/collections\/omega-3-vetzuren\"\u003eOmega 3\u003c\/a\u003e: for those who want to supplement their routine with fish oil or algae oil.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"faq\"\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is MSM?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMSM (methylsulfonylmethane) is an organic sulphur compound. It occurs in small amounts in vegetables, fruit, milk, coffee and tea. As a supplement, it is usually taken in capsules or as a powder.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow much MSM should I take per day?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFollow the dosage on the label. For Plantforce Vegan MSM, that is 2 to 3 capsules per day (1,600–2,400 mg). For Glucosamine Chondroitin MSM from Doctor's Best, it is 4 capsules per day (1,000 mg MSM).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is OptiMSM®?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOptiMSM® is a brand name for MSM that is purified by distillation. It is contained in Glucosamine Chondroitin MSM from Doctor's Best.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs MSM vegan?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMSM itself is. Plantforce Vegan MSM is fully vegan. Glucosamine Chondroitin MSM from Doctor's Best is not: the glucosamine comes from shellfish and the chondroitin from beef.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen should I take MSM?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePreferably with a meal and a glass of water. Optionally split the daily dose over two moments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes MSM have side effects?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn studies, MSM is well tolerated at common dosages; mild gastrointestinal complaints are sometimes reported. If pregnant, breastfeeding or taking medication, consult your doctor first.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"bronnen\"\u003eSources\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eButawan M, Benjamin RL, Bloomer RJ (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients 9(3):290.\u003c\/li\u003e\n\u003cli\u003eKim LS et al. (2006). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 14(3):286–294.\u003c\/li\u003e\n\u003cli\u003eBrien S et al. (2008). Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis. Osteoarthritis Cartilage 16(11):1277–1288.\u003c\/li\u003e\n\u003cli\u003evan der Merwe M, Bloomer RJ (2016). The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise. J Sports Med 2016:7498359.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This text is for informational purposes only and does not replace medical advice. MSM is a food supplement, not a medicine. If in doubt or if you take medication, we recommend consulting a doctor or orthomolecular therapist first.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/article\u003e","products":[{"product_id":"plantforce-vegan-msm-200-caps","title":"Vegan MSM – 200 capsules","description":"\u003cp\u003ePlant-based sulphur in its purest form. Plantforce Vegan MSM contains 800 mg methylsulfonylmethane (MSM) of plant origin per capsule — without additives, suitable for vegans. 200 capsules, enough for 67–100 daily doses.\u003c\/p\u003e","brand":"Plantforce","offers":[{"title":"Default Title","offer_id":56768660275545,"sku":"10000","price":34.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/plantforce-msm-200-capsules.jpg?v=1774873280"},{"product_id":"doctors-best-glucosamine-chondroitin-msm-240-caps","title":"Glucosamine Chondroitin MSM – 240 capsules","description":"\u003cp\u003e\u003cspan\u003eDoctor's Best Glucosamine Chondroitin MSM brings together three popular building blocks — glucosamine, chondroitin, and MSM — in one capsule. The MSM component comes from OptiMSM®, a distilled form produced by Bergstrom Nutrition. For those who prefer these three ingredients in one formula rather than in three separate containers. Jar of 240 capsules, sufficient for 60 days at 4 capsules per day.\u003c\/span\u003e\u003c\/p\u003e","brand":"Doctor's Best","offers":[{"title":"Default Title","offer_id":56769254981977,"sku":"9258","price":45.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/753950000810V-BFP-V6-050124_b83628ce-02d2-4cfc-ac1e-d8021270f15d.webp?v=1780580174"},{"product_id":"doctors-best-glucosamine-chondroitin-msm-with-optimsm-360-caps","title":"Glucosamine Chondroitin MSM with OptiMSM® – 360 capsules","description":"\u003cp\u003e\u003cspan\u003eDoctor's Best Glucosamine Chondroitin MSM with OptiMSM® is the value jar of the same formula, with multi-stage distilled OptiMSM® whose purity is checked at every production step. Three widely used building blocks in one capsule — glucosamine, chondroitin and MSM. For those already used to this formula who want to switch to the larger supply pack. Jar of 360 capsules, enough for 90 days at 4 capsules per day.\u003c\/span\u003e\u003c\/p\u003e","brand":"Doctor's Best","offers":[{"title":"Default Title","offer_id":56769649541465,"sku":"DB3644","price":69.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/doctor-s-best-glucosamine-chondroitin-msm-with-optimsm-360-caps-1.jpg?v=1773932815"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/collections\/plantforce-msm-200-capsules-2.jpg?v=1776084574","url":"https:\/\/www.plenthera.com\/en-lu\/collections\/msm.oembed","provider":"Plenthera","version":"1.0","type":"link"}