{"title":"Protease","description":"\u003cp\u003e\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"BreadcrumbList\",\n  \"itemListElement\": [\n    { \"@type\": \"ListItem\", \"position\": 1, \"name\": \"Home\", \"item\": \"https:\/\/plenthera.com\/\" },\n    { \"@type\": \"ListItem\", \"position\": 2, \"name\": \"Categorieën\", \"item\": \"https:\/\/plenthera.com\/collections\/\" },\n    { \"@type\": \"ListItem\", \"position\": 3, \"name\": \"Protease\", \"item\": \"https:\/\/plenthera.com\/collections\/protease\/\" }\n  ]\n}\n\u003c\/script\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"CollectionPage\",\n  \"name\": \"Protease bij Plenthera\",\n  \"description\": \"Premium protease — eiwit-afbrekende enzymen voor eiwit-vertering en sport-herstel. Los of in enzym-complex.\",\n  \"url\": \"https:\/\/plenthera.com\/collections\/protease\/\",\n  \"inLanguage\": \"nl-NL\",\n  \"isPartOf\": { \"@type\": \"WebSite\", \"name\": \"Plenthera\", \"url\": \"https:\/\/plenthera.com\/\" },\n  \"about\": { \"@type\": \"Thing\", \"name\": \"Protease\", \"description\": \"Protease is een verzamelnaam voor enzymen die eiwit afbreken tot opneembare aminozuren en peptiden.\" }\n}\n\u003c\/script\u003e \u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\"@type\":\"Question\",\"name\":\"Wat is protease?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Eiwit-afbrekend enzym (verzamelnaam). Pepsine, trypsine, chymotrypsine zijn lichaamseigen; bromelaïne en papaïne zijn plantaardig.\"}},\n    {\"@type\":\"Question\",\"name\":\"Wanneer protease innemen?\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Bij eiwit-rijke maaltijden. Voor sport-herstel ook tussen maaltijden op lege maag.\"}}\n  ]\n}\n\u003c\/script\u003e\u003c\/p\u003e\n\u003carticle\u003e\n\u003cp\u003e\u003cem\u003eWritten by the Plenthera team (orthomolecularly trained). Scientifically reviewed in April 2026. Last updated: April 30, 2026.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eProtease is not a single enzyme but a family — pepsin, trypsin, bromelain, papain — each breaking down protein into absorbable amino acids and peptides. For those with a high-protein diet (athletes, elderly, meat-heavy diet), protease supplementation can provide support. At Plenthera, you'll find \u003ca href=\"\/en\/collections\/protease\"\u003eprotease\u003c\/a\u003e as individual capsules or in enzyme complexes.\u003c\/p\u003e\n\u003cnav aria-label=\"Table of Contents\"\u003e\n\u003ch2\u003eTable of Contents\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003e\u003ca href=\"#vergelijking\"\u003eWhich protease is right for you?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wat-is-protease\"\u003eWhat is protease?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#wetenschap\"\u003eScience and EFSA status\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#vormen\"\u003eThe protease forms at Plenthera\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#hoe-gebruik\"\u003eHow to use protease?\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#mythes\"\u003eMyths and misunderstandings about protease\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#combineren\"\u003eCombining protease with other supplements\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#faq\"\u003eFrequently asked questions\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#bronnen\"\u003eSources\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/nav\u003e\n\u003csection\u003e\n\u003ch2 id=\"vergelijking\"\u003eWhich protease is right for you?\u003c\/h2\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eBest for\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eProtease mix (separate)\u003c\/td\u003e\n\u003ctd\u003eSpecific protein digestion\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIn enzyme complex\u003c\/td\u003e\n\u003ctd\u003eBroad digestion\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBromelain (separate)\u003c\/td\u003e\n\u003ctd\u003eProtein + inflammatory theme\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wat-is-protease\"\u003eWhat is protease?\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eProtease is a collective term for enzymes that break down protein — pepsin, trypsin, and chymotrypsin (body's own), bromelain (from pineapple), papain (from papaya).\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eProtein digestion begins in the stomach with pepsin (activated by stomach acid), continues in the small intestine with trypsin and chymotrypsin from the pancreas. For those who eat a lot of protein — athletes with high protein intake, meat-heavy diet, elderly with reduced endogenous production — protease supplementation can reduce the burden on their own system.\u003c\/p\u003e\n\u003cp\u003eIn supplements, multiple proteases are often combined for a broad pH range. Plant-based bromelain (from pineapple) primarily works in the gut; pepsin works in stomach acid. A protease mix covers the entire digestive tract.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"wetenschap\"\u003eScience and EFSA status\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.efsa.europa.eu\/en\/topics\/topic\/health-claims\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eEFSA\u003c\/a\u003e has not recognized specific claims for protease. We do not make efficacy claims.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"vormen\"\u003eThe protease forms at Plenthera\u003c\/h2\u003e\n\u003ch3\u003eProtease separately (capsules)\u003c\/h3\u003e\n\u003cp\u003eFor specific protein digestion. Often contains a protease mix.\u003c\/p\u003e\n\u003ch3\u003eProtease in enzyme complex\u003c\/h3\u003e\n\u003cp\u003ePart of a broad-spectrum formula.\u003c\/p\u003e\n\u003ch3\u003eBromelain (pineapple protease)\u003c\/h3\u003e\n\u003cp\u003eSeparate category — view our \u003ca href=\"\/en\/collections\/bromelaine\"\u003ebromelain category\u003c\/a\u003e.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"hoe-gebruik\"\u003eHow to use protease?\u003c\/h2\u003e\n\u003cp\u003eSimple basic approach for protease:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eWith protein-rich meals — 1-2 capsules.\u003c\/li\u003e\n\u003cli\u003eFor sports recovery: between meals, on an empty stomach.\u003c\/li\u003e\n\u003cli\u003eFor broad coverage: enzyme complex.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"mythes\"\u003eMyths and misunderstandings about protease\u003c\/h2\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 1: \"Protease makes protein more absorbable for muscle growth.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eHealthy individuals digest protein well on their own. For reduced endogenous production, supplementation can help.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 2: \"Higher protease dosages lead to more amino acids.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eAbove a certain dosage, extra protease does not translate to extra absorption.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eMyth 3: \"Protease and bromelain are the same.\"\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eBromelain is a protease — a specific one from pineapple. Usually, multiple proteases are mixed.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"combineren\"\u003eCombining protease with other supplements\u003c\/h2\u003e\n\u003cp\u003eProtease is often combined. Common combinations:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/bromelaine\"\u003eBromelain\u003c\/a\u003e: additional protein enzyme with an inflammatory theme.\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/ondersteuning\"\u003eDigestive enzyme complex\u003c\/a\u003e: broad coverage.\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/vegan-proteine\"\u003eVegan protein\u003c\/a\u003e: for sports protein cluster.\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"\/en\/collections\/ondersteuning\"\u003eProbiotics\u003c\/a\u003e: gut theme.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"faq\"\u003eFrequently asked questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eProtein-breaking enzyme (collective term).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhen to take protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWith protein-rich meals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtease for sports?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor recovery: between meals. For meals: with protein.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow much protease per day?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFollow label instructions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is HUT?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUnit for protease activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eVegan protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMicrobial\/plant-based: yes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDifference between bromelain and protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBromelain is a specific protease from pineapple.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDoes protease have side effects?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGenerally well tolerated.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePlant-based vs animal protease?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePlant-based: vegan. Animal (pancreatin): classic.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtease for bloating?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCan help with protein-related discomfort.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection\u003e\n\u003ch2 id=\"bronnen\"\u003eSources\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.efsa.europa.eu\/en\/topics\/topic\/health-claims\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eEFSA Regulation (EU) 432\/2012\u003c\/a\u003e — no overarching enzyme claims; individual claims limited.\u003c\/li\u003e\n\u003cli\u003eRoxas M., \"The role of enzyme supplementation in digestive disorders\", Altern Med Rev (2008).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eDisclaimer:\u003c\/strong\u003e This text is for informational purposes only and does not replace medical advice. Protease is a dietary supplement, not a medicine. In case of doubt or if you are taking medication, we recommend consulting a doctor or orthomolecular therapist first.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/article\u003e","products":[{"product_id":"arthur-andrew-neprinol-afd-150-caps","title":"Neprinol AFD® - 150 capsules","description":"\u003cp\u003eNeprinol AFD® is an enzyme complex in capsules with nattokinase, serrapeptase, proteinases, papain, bromelain and lipase, supplemented with magnesium, amla extract, rutin and coenzyme Q10. The formula is available in acid-resistant Acid Armor capsules made of vegetable cellulose, without coating.\u003c\/p\u003e\n\u003cp\u003eAcid Armor Capsule • 150 capsules per package • Non-GMO • Kosher • Vegetarian\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767386026329,"sku":"AAM1071","price":79.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/aam-neprinol-150-capsules-1.jpg?v=1773917372"},{"product_id":"arthur-andrew-neprinol-afd-300-caps","title":"Neprinol AFD® Enzyme Complex — 300 Capsules","description":"\u003cp\u003eNeprinol AFD® is an enzyme complex in capsules with nattokinase, serrapeptase, proteinases, papain, bromelain, and lipase, supplemented with magnesium, amla extract, rutin, and coenzyme Q10. The formula is available in acid-resistant Acid Armor capsules made of vegetable cellulose, without coating.\u003c\/p\u003e\n\u003cp\u003eAcid Armor Capsule • 300 capsules per package • Non-GMO • Kosher • Vegetarian\u003c\/p\u003e","brand":"Arthur Andrew Medical","offers":[{"title":"Default Title","offer_id":56767386845529,"sku":"AAM1070","price":139.95,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0941\/6127\/3177\/files\/aam-neprinol-300-capsules.jpg?v=1773917446"},{"product_id":"arthur-andrew-serretia-180-caps","title":"Serretia® – 180 capsules | Pure Serrapeptase Formula – Arthur Andrew","description":"\u003cp\u003eSerretia® is a dietary supplement containing only serrapeptase (250,000 SPU per 2 capsules) in vegetarian Acid Armor capsules from Arthur Andrew Medical. 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