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Fatigue as a Vegan: 5 Nutrients to Keep an Eye On

A well-composed plant-based diet can be rich in fiber, antioxidants, and healthy fats — and in many ways more beneficial than an average Western diet. However, there are a number of nutrients that are concentrated in animal products and less abundant in plant-based foods. For those who eat entirely plant-based (or mostly plant-based), these are the substances to watch out for — especially if fatigue is a recurring theme. In this article: five nutrients that require extra attention for vegans, how to recognize deficiencies, and how to supplement them specifically.
Vermoeidheid als veganist: 5 voedingsstoffen om in de gaten te houden

Fatigue in vegans: B12 and iron first

Most vegans eat a varied diet and have no complaints—especially with good planning. But if fatigue persists, or develops over a longer period, a nutrient check is advisable. A few substances require more conscious planning in a plant-based diet: B12, iron, B vitamins more broadly, vitamin D, and iodine.

Below, we will go through them one by one.

1. Vitamin B12 — the most important check for every vegan 

Vitamin B12 occurs naturally almost exclusively in animal products. Those who eat a completely plant-based diet will get hardly any B12 without supplementation or fortified foods. A deficiency develops insidiously and can manifest as fatigue, concentration problems, tingling, or mood issues. For vegans, a B12 supplement is almost always necessary—fortified products alone are often insufficient.

2. Iron — extra vigilance for menstruating women 

Iron in plant-based foods (non-heme iron) is absorbed less well than iron from meat (heme iron). This does not mean that vegans necessarily have a deficiency—but it does mean that a higher intake is needed to achieve the same status. For menstruating women, women who want to become pregnant, and people with intense athletic activity, an iron check is particularly useful.

How do you improve plant-based iron absorption? 

  • Combine with vitamin C — citrus, bell peppers, or a glass of orange juice with an iron-rich meal significantly increases absorption.
  • Avoid tea/coffee with meals — tannins inhibit iron absorption; drink 1-2 hours before or after.
  • Soak or ferment legumes and grains — reduces phytates that bind iron.
  • Combine with sauerkraut or citrus — organic acids improve absorption.

If a deficiency is suspected: have your ferritin (iron stores) and hemoglobin measured by your GP. Based on these results, appropriate supplementation can be determined.

B vitamins broadly and vitamin D

Besides B12, other B vitamins also play an important role in energy metabolism and the nervous system. In plant-based foods, most B vitamins can be found in whole grains, legumes, seeds, and vegetables — but with unbalanced eating patterns, B2 (riboflavin) and B6, among others, can be suboptimal.

A vegan B-complex with the active forms of B vitamins (such as methylcobalamin for B12 and methylfolate for B11) is an efficient basis for many plant-based eaters — all B vitamins in one capsule, without having to combine separate supplements.

Source:EU Register on nutrition and health claims(Regulation (EU) 432/2012 — officially authorised health claims). 

4. Vitamin D — for everyone, with extra attention for vegans 

Vitamin D is mainly found in food in fatty fish, eggs, and (fortified) dairy — none of which are plant-based sources. For vegans, a D3 supplement is practically necessary in winter, and for many people, year-round. Please note: explicitly choose plant-based (vegan) vitamin D3, extracted from lichen. "Standard" D3 supplements often come from lanolin (sheep's fat). A vegan D3 + K2 combination such as Arthur Andrew KD Ultra(full-spectrum K2+ vegan D3 from lichen) is an efficient approach for vegans in one capsule.

Frequently Asked Questions about fatigue on a vegan diet

Iodine, magnesium, zinc, and omega-3

The Often Forgotten Nutrients

Iodine is essential for thyroid function, and the thyroid regulates your entire energy metabolism. Those who do not eat fish, iodine-containing bread (iodised salt), or seaweed risk a deficiency. Symptoms: fatigue, feeling cold, slow bowel movements. Vegan iodine sources: seaweed (kelp, nori),Irish Sea Moss, and to a limited extent, iodised salt. A vegan iodine supplement based on seaweed—such as KiKi HealthOrganic Sea Kelp or Organic Irish Sea Moss—is a targeted supplement for those who do not eat seaweed. If you suspect a deficiency, have your TSH and possibly iodine excretion measured by your GP.

What about magnesium, zinc, and omega-3? 

In addition to the five main points, there are three honourable mentions:

  • Magnesium—usually sufficient through plant-based foods (nuts, seeds, legumes), but often extra beneficial during stress or exercise (see blog May #4 and June #2).
  • Zinc—readily available in plant-based foods (nuts, seeds, legumes), though slightly less absorbable due to phytates. Soaking/fermenting helps.
  • Omega-3 (EPA/DHA)—plant-based foods only contain ALA (flaxseed, walnuts, chia seeds), and the conversion to EPA/DHA is limited. An algae omega-3 supplement (for example, Plantforce Vegan Omega-3 Algae Oil—own brand, or Nordic Naturals Algae Omega) is a targeted supplement for vegans.

Eating plant-based and staying energetic go hand in hand—provided you consciously incorporate a few nutrients into your planning. B12 is indispensable for almost every vegan; iron and B vitamins are more broadly important, and vitamin D and iodine deserve extra attention. If you experience persistent fatigue: don't just assume it's "part of the deal"—have your status measured and develop a suitable plan with a doctor or orthomolecular therapist. With the right supplement foundation, a vegan diet can be fully supported.

Disclaimer:This article is for informational purposes only and does not replace medical advice. A dietary supplement is not a substitute for a varied and balanced diet and a healthy lifestyle. If in doubt or taking medication: consult a doctor or pharmacist. Do not exceed the recommended daily dose. Keep out of reach of young children.